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Dysregulated Sp1/miR-130b-3p/HOXA5 axis contributes to tumor angiogenesis and progression of hepatocellular carcinoma

Angiogenesis, one of the hallmarks of cancer, is essential for both tumor growth and metastasis. However, its molecular mechanisms in hepatocellular carcinoma (HCC) are largely unknown. Here, we report the role of HOXA5 in tumor angiogenesis of HCC. Methods: The expression of miR-130b-3p and HOXA5 w...

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Vydáno v:Theranostics
Hlavní autoři: Liao, Yadi, Wang, Chenwei, Yang, Zhiwen, Liu, Wenwu, Yuan, Yichuan, Li, Kai, Zhang, Yuanping, Wang, Yongjin, Shi, Yunxing, Qiu, Yuxiong, Zuo, Dinglan, He, Wei, Qiu, Jiliang, Guan, Xinyuan, Yuan, Yunfei, Li, Binkui
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196310/
https://ncbi.nlm.nih.gov/pubmed/32373208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.43640
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