Elafin promotes tumour metastasis and attenuates the anti-metastatic effects of erlotinib via binding to EGFR in hepatocellular carcinoma

BACKGROUND: Elafin is a serine protease inhibitor critical for host defence. We previously reported that Elafin was associated with the recurrence of early-stage hepatocellular carcinoma (HCC) after surgery. However, the exact role of Elafin in HCC remains obscure. METHODS: HCC tissue microarrays we...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Wang, Chenwei, Liao, Yadi, He, Wei, Zhang, Hong, Zuo, Dinglan, Liu, Wenwu, Yang, Zhiwen, Qiu, Jiliang, Yuan, Yichuan, Li, Kai, Zhang, Yuanping, Wang, Yongjin, Shi, Yunxing, Qiu, Yuxiong, Gao, Song, Yuan, Yunfei, Li, Binkui
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7995733/
https://ncbi.nlm.nih.gov/pubmed/33771199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-01904-y
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