Xanthohumol suppresses glioblastoma via modulation of Hexokinase 2 -mediated glycolysis

Deregulation of aerobic glycolysis is a common phenomenon in human cancers, including glioblastoma (GBM). In the present study, we demonstrated that the natural compound xanthohumol has a profound anti-tumor effect on GBM via direct inhibition of glycolysis. Xanthohumol suppressed cell proliferation...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Cancer
Main Authors: Yuan, Jian, Peng, Gang, Xiao, Gelei, Yang, Zhuanyi, Huang, Jun, Liu, Qing, Yang, Zhiquan, Liu, Dingyang
Format: Artigo
Jezik:Inglês
Izdano: Ivyspring International Publisher 2020
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196271/
https://ncbi.nlm.nih.gov/pubmed/32368287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.33045
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