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Xanthohumol inhibits colorectal cancer cells via downregulation of Hexokinases II-mediated glycolysis
Deregulation of glycolysis is a common phenomenon in human colorectal cancer (CRC). In the present study, we reported that Hexokinase 2 (HK2) is overexpressed in human CRC tissues and cell lines, knockout of HK2 inhibited cell proliferation, colony formation, and xenograft tumor growth. We demonstra...
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| Publicado no: | Int J Biol Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Ivyspring International Publisher
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6775317/ https://ncbi.nlm.nih.gov/pubmed/31595166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.37481 |
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