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Xanthohumol suppresses glioblastoma via modulation of Hexokinase 2 -mediated glycolysis

Deregulation of aerobic glycolysis is a common phenomenon in human cancers, including glioblastoma (GBM). In the present study, we demonstrated that the natural compound xanthohumol has a profound anti-tumor effect on GBM via direct inhibition of glycolysis. Xanthohumol suppressed cell proliferation...

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Detalhes bibliográficos
Publicado no:J Cancer
Main Authors: Yuan, Jian, Peng, Gang, Xiao, Gelei, Yang, Zhuanyi, Huang, Jun, Liu, Qing, Yang, Zhiquan, Liu, Dingyang
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196271/
https://ncbi.nlm.nih.gov/pubmed/32368287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.33045
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