Dehydrocostus lactone inhibits NFATc1 via regulation of IKK, JNK, and Nrf2, thereby attenuating osteoclastogenesis

Excessive and hyperactive osteoclast activity causes bone diseases such as osteoporosis and periodontitis. Thus, the regulation of osteoclast differentiation has clinical implications. We recently reported that dehydrocostus lactone (DL) inhibits osteoclast differentiation by regulating a nuclear fa...

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Detaylı Bibliyografya
Yayımlandı:BMB Rep
Asıl Yazarlar: Lee, Hye In, Lee, Gong-Rak, Lee, Jiae, Kim, Narae, Kwon, Minjeong, Kim, Hyun Jin, Kim, Nam Young, Park, Jin Ha, Jeong, Woojin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Korean Society for Biochemistry and Molecular Biology 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196184/
https://ncbi.nlm.nih.gov/pubmed/31964469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2020.53.4.220
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