Accelerated Lactate Dehydrogenase Activity Potentiates Osteoclastogenesis via NFATc1 Signaling

Osteoclasts seem to be metabolic active during their differentiation and bone-resorptive activation. However, the functional role of lactate dehydrogenase (LDH), a tetrameric enzyme consisting of an A and/or B subunit that catalyzes interconversion of pyruvate to lactate, in RANKL-induced osteoclast...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Ahn, Heejin, Lee, Kyunghee, Kim, Jin Man, Kwon, So Hyun, Lee, Seoung Hoon, Lee, Soo Young, Jeong, Daewon
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831772/
https://ncbi.nlm.nih.gov/pubmed/27077737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153886
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