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Regulation of TFEB activity and its potential as a therapeutic target against kidney diseases
The transcription factor EB (TFEB) regulates the expression of target genes bearing the Coordinated Lysosomal Expression and Regulation (CLEAR) motif, thereby modulating autophagy and lysosomal biogenesis. Furthermore, TFEB can bind to the promoter of autophagy-associated genes and induce the format...
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| Publicado no: | Cell Death Discov |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7195473/ https://ncbi.nlm.nih.gov/pubmed/32377395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-020-0265-4 |
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