Regulation of TFEB activity and its potential as a therapeutic target against kidney diseases

The transcription factor EB (TFEB) regulates the expression of target genes bearing the Coordinated Lysosomal Expression and Regulation (CLEAR) motif, thereby modulating autophagy and lysosomal biogenesis. Furthermore, TFEB can bind to the promoter of autophagy-associated genes and induce the format...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cell Death Discov
Asıl Yazarlar: Zhang, Weihuang, Li, Xiaoyu, Wang, Shujun, Chen, Yanse, Liu, Huafeng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Review Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7195473/
https://ncbi.nlm.nih.gov/pubmed/32377395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-020-0265-4
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