TFEB, a potential therapeutic target for osteoarthritis via autophagy regulation

The blockage of autophagic flux in chondrocytes has been considered as a major reason for the excessive cellular apoptosis and senescence in osteoarthritis (OA) development; however, the molecular mechanism and therapeutic strategy for interrupted autophagic flux is still not clear. Most recently, t...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Zheng, Gang, Zhan, Yu, Li, Xiaobin, Pan, Zongyou, Zheng, Fanghong, Zhang, Zengjie, Zhou, Yifei, Wu, Yaosen, Wang, Xiangyang, Gao, Weiyang, Xu, Huazi, Tian, Naifeng, Zhang, Xiaolei
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6113230/
https://ncbi.nlm.nih.gov/pubmed/30154423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0909-y
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