A novel neurodegenerative spectrum disorder in patients with MLKL deficiency

Mixed lineage kinase domain-like (MLKL) is the main executor of necroptosis, an inflammatory form of programmed cell death. Necroptosis is implicated in combating infections, but also in contributing to numerous other clinical conditions, including cardiovascular diseases and neurodegenerative disor...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Faergeman, Soren L., Evans, Hayley, Attfield, Kathrine E., Desel, Christiane, Kuttikkatte, Subita Balaram, Sommerlund, Mette, Jensen, Lise Torp, Frokiaer, Jorgen, Friese, Manuel A., Matthews, Paul M., Luchtenborg, Christian, Brügger, Britta, Oturai, Annette Bang, Dendrou, Calliope A., Fugger, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7195448/
https://ncbi.nlm.nih.gov/pubmed/32358523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2494-0
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