Photoactivatable Cre recombinase 3.0 for in vivo mouse applications

Optogenetic genome engineering tools enable spatiotemporal control of gene expression and provide new insight into biological function. Here, we report the new version of genetically encoded photoactivatable (PA) Cre recombinase, PA-Cre 3.0. To improve PA-Cre technology, we compare light-dimerizatio...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Morikawa, Kumi, Furuhashi, Kazuhiro, de Sena-Tomas, Carmen, Garcia-Garcia, Alvaro L., Bekdash, Ramsey, Klein, Alison D., Gallerani, Nicholas, Yamamoto, Hannah E., Park, Seon-Hye E., Collins, Grant S., Kawano, Fuun, Sato, Moritoshi, Lin, Chyuan-Sheng, Targoff, Kimara L., Au, Edmund, Salling, Michael C., Yazawa, Masayuki
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7195411/
https://ncbi.nlm.nih.gov/pubmed/32358538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16030-0
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