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Achieving tight control of a photoactivatable Cre recombinase gene switch: new design strategies and functional characterization in mammalian cells and rodent

A common mechanism for inducibly controlling protein function relies on reconstitution of split protein fragments using chemical or light-induced dimerization domains. A protein is split into fragments that are inactive on their own, but can be reconstituted after dimerization. As many split protein...

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Podrobná bibliografie
Vydáno v:Nucleic Acids Res
Hlavní autoři: Meador, Kyle, Wysoczynski, Christina L, Norris, Aaron J, Aoto, Jason, Bruchas, Michael R, Tucker, Chandra L
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6753482/
https://ncbi.nlm.nih.gov/pubmed/31287871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz585
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