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Natural variability in seizure frequency: implications for trials and placebo
BACKGROUND: Changes in patient-reported seizure frequencies are the gold standard used to test efficacy of new treatments in randomized controlled trials (RCTs). Recent analyses of patient seizure diary data suggest that the placebo response may be attributable to natural fluctuations in seizure fre...
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| Publicado no: | Epilepsy Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7194486/ https://ncbi.nlm.nih.gov/pubmed/32172145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eplepsyres.2020.106306 |
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