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Investigating the effect of dependence between conditions with Bayesian Linear Mixed Models for motif activity analysis

MOTIVATION: Cellular identity and behavior is controlled by complex gene regulatory networks. Transcription factors (TFs) bind to specific DNA sequences to regulate the transcription of their target genes. On the basis of these TF motifs in cis-regulatory elements we can model the influence of TFs o...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lederer, Simone, Heskes, Tom, van Heeringen, Simon J., Albers, Cornelis A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7194367/
https://ncbi.nlm.nih.gov/pubmed/32357166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0231824
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