Direct Comparison of Mononucleated and Binucleated Cardiomyocytes Reveals Molecular Mechanisms Underlying Distinct Proliferative Competencies

The mammalian heart is incapable of regenerating a sufficient number of cardiomyocytes to ameliorate the loss of contractile muscle after acute myocardial injury. Several reports have demonstrated that mononucleated cardiomyocytes are more responsive than are binucleated cardiomyocytes to proprolife...

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Publicat a:Cell Rep
Autors principals: Windmueller, Rebecca, Leach, John P., Babu, Apoorva, Zhou, Su, Morley, Michael P., Wakabayashi, Aoi, Petrenko, Nataliya B., Viatour, Patrick, Morrisey, Edward E.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7194103/
https://ncbi.nlm.nih.gov/pubmed/32130910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.02.034
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