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Structure of the N-terminal domain of ClpC1 in complex with the antituberculosis natural product ecumicin reveals unique binding interactions

The biological processes related to protein homeostasis in Mycobacterium tuberculosis, the etiologic agent of tuberculosis, have recently been established as critical pathways for therapeutic intervention. Proteins of particular interest are ClpC1 and the ClpC1–ClpP1–ClpP2 proteasome complex. The st...

詳細記述

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書誌詳細
出版年:Acta Crystallogr D Struct Biol
主要な著者: Wolf, Nina M., Lee, Hyun, Zagal, Daniel, Nam, Joo-Won, Oh, Dong-Chan, Lee, Hanki, Suh, Joo-Won, Pauli, Guido F., Cho, Sanghyun, Abad-Zapatero, Celerino
フォーマット: Artigo
言語:Inglês
出版事項: International Union of Crystallography 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7193532/
https://ncbi.nlm.nih.gov/pubmed/32355042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798320004027
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