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Structure of the N-terminal domain of ClpC1 in complex with the antituberculosis natural product ecumicin reveals unique binding interactions

The biological processes related to protein homeostasis in Mycobacterium tuberculosis, the etiologic agent of tuberculosis, have recently been established as critical pathways for therapeutic intervention. Proteins of particular interest are ClpC1 and the ClpC1–ClpP1–ClpP2 proteasome complex. The st...

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Dades bibliogràfiques
Publicat a:Acta Crystallogr D Struct Biol
Autors principals: Wolf, Nina M., Lee, Hyun, Zagal, Daniel, Nam, Joo-Won, Oh, Dong-Chan, Lee, Hanki, Suh, Joo-Won, Pauli, Guido F., Cho, Sanghyun, Abad-Zapatero, Celerino
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7193532/
https://ncbi.nlm.nih.gov/pubmed/32355042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798320004027
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