Iron overload inhibits self‐renewal of human pluripotent stem cells via DNA damage and generation of reactive oxygen species

Iron overload affects the cell cycle of various cell types, but the effect of iron overload on human pluripotent stem cells has not yet been reported. Here, we show that the proliferation capacities of human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs) were signific...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Han, Zhenbo, Xu, Zihang, Chen, Lei, Ye, Danyu, Yu, Yang, Zhang, Ying, Cao, Yang, Djibril, Bamba, Guo, Xiaofei, Gao, Xinlu, Zhang, Wenwen, Yu, Meixi, Liu, Shenzhen, Yan, Gege, Jin, Mengyu, Huang, Qi, Wang, Xiuxiu, Hua, Bingjie, Feng, Chao, Yang, Fan, Ma, Wenya, Liu, Yu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7193162/
https://ncbi.nlm.nih.gov/pubmed/32053740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12811
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