Iron overload inhibits self‐renewal of human pluripotent stem cells via DNA damage and generation of reactive oxygen species

Iron overload affects the cell cycle of various cell types, but the effect of iron overload on human pluripotent stem cells has not yet been reported. Here, we show that the proliferation capacities of human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs) were signific...

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Dades bibliogràfiques
Publicat a:FEBS Open Bio
Autors principals: Han, Zhenbo, Xu, Zihang, Chen, Lei, Ye, Danyu, Yu, Yang, Zhang, Ying, Cao, Yang, Djibril, Bamba, Guo, Xiaofei, Gao, Xinlu, Zhang, Wenwen, Yu, Meixi, Liu, Shenzhen, Yan, Gege, Jin, Mengyu, Huang, Qi, Wang, Xiuxiu, Hua, Bingjie, Feng, Chao, Yang, Fan, Ma, Wenya, Liu, Yu
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7193162/
https://ncbi.nlm.nih.gov/pubmed/32053740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12811
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