Iron overload inhibits self‐renewal of human pluripotent stem cells via DNA damage and generation of reactive oxygen species

Iron overload affects the cell cycle of various cell types, but the effect of iron overload on human pluripotent stem cells has not yet been reported. Here, we show that the proliferation capacities of human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs) were signific...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:FEBS Open Bio
Prif Awduron: Han, Zhenbo, Xu, Zihang, Chen, Lei, Ye, Danyu, Yu, Yang, Zhang, Ying, Cao, Yang, Djibril, Bamba, Guo, Xiaofei, Gao, Xinlu, Zhang, Wenwen, Yu, Meixi, Liu, Shenzhen, Yan, Gege, Jin, Mengyu, Huang, Qi, Wang, Xiuxiu, Hua, Bingjie, Feng, Chao, Yang, Fan, Ma, Wenya, Liu, Yu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2020
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7193162/
https://ncbi.nlm.nih.gov/pubmed/32053740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12811
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg