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CAMIO: a transgenic CRISPR pipeline to create diverse targeted genome deletions in Drosophila

The genome is the blueprint for an organism. Interrogating the genome, especially locating critical cis-regulatory elements, requires deletion analysis. This is conventionally performed using synthetic constructs, making it cumbersome and non-physiological. Thus, we created Cas9-mediated Arrayed Mut...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Chen, Hui-Min, Marques, Jorge Garcia, Sugino, Ken, Wei, Dingjun, Miyares, Rosa Linda, Lee, Tzumin
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7192631/
https://ncbi.nlm.nih.gov/pubmed/32187363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa177
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