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The genomic landscape of 8-oxodG reveals enrichment at specific inherently fragile promoters

8-Oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG) is the most common marker of oxidative stress and its accumulation within the genome has been associated with major human health issues such as cancer, aging, cardiovascular and neurodegenerative diseases. The characterization of the different genomic si...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Gorini, Francesca, Scala, Giovanni, Di Palo, Giacomo, Dellino, Gaetano Ivan, Cocozza, Sergio, Pelicci, Pier Giuseppe, Lania, Luigi, Majello, Barbara, Amente, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7192600/
https://ncbi.nlm.nih.gov/pubmed/32198884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa175
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