The genomic landscape of 8-oxodG reveals enrichment at specific inherently fragile promoters

8-Oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG) is the most common marker of oxidative stress and its accumulation within the genome has been associated with major human health issues such as cancer, aging, cardiovascular and neurodegenerative diseases. The characterization of the different genomic si...

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Библиографические подробности
Опубликовано в: :Nucleic Acids Res
Главные авторы: Gorini, Francesca, Scala, Giovanni, Di Palo, Giacomo, Dellino, Gaetano Ivan, Cocozza, Sergio, Pelicci, Pier Giuseppe, Lania, Luigi, Majello, Barbara, Amente, Stefano
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2020
Предметы:
Genome Integrity, Repair and Replication
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7192600/
https://ncbi.nlm.nih.gov/pubmed/32198884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa175
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