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The genomic landscape of 8-oxodG reveals enrichment at specific inherently fragile promoters

8-Oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG) is the most common marker of oxidative stress and its accumulation within the genome has been associated with major human health issues such as cancer, aging, cardiovascular and neurodegenerative diseases. The characterization of the different genomic si...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Gorini, Francesca, Scala, Giovanni, Di Palo, Giacomo, Dellino, Gaetano Ivan, Cocozza, Sergio, Pelicci, Pier Giuseppe, Lania, Luigi, Majello, Barbara, Amente, Stefano
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7192600/
https://ncbi.nlm.nih.gov/pubmed/32198884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa175
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