The genomic landscape of 8-oxodG reveals enrichment at specific inherently fragile promoters

8-Oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG) is the most common marker of oxidative stress and its accumulation within the genome has been associated with major human health issues such as cancer, aging, cardiovascular and neurodegenerative diseases. The characterization of the different genomic si...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Gorini, Francesca, Scala, Giovanni, Di Palo, Giacomo, Dellino, Gaetano Ivan, Cocozza, Sergio, Pelicci, Pier Giuseppe, Lania, Luigi, Majello, Barbara, Amente, Stefano
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Genome Integrity, Repair and Replication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7192600/
https://ncbi.nlm.nih.gov/pubmed/32198884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa175
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