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Plasma pyroglutamate‐modified amyloid beta differentiates amyloid pathology

INTRODUCTION: Pyroglutamate‐modified amyloid β (Aβ(pE3)) could be a biomarker for Aβ plaque pathology in the brain. An ultra‐high‐sensitive assay is needed for detecting Aβ(pE3‐40). METHODS: Immunomagnetic reduction was used for quantification of Aβ(pE3‐40) in plasma from 46 participants. The concen...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement (Amst)
Main Authors: Wang, Pei‐Ning, Lin, Kun‐Ju, Liu, Huei‐Chun, Andreasson, Ulf, Blennow, Kaj, Zetterberg, Henrik, Yang, Shieh‐Yueh
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7191392/
https://ncbi.nlm.nih.gov/pubmed/32363230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dad2.12029
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