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Bispecific human IL2‐CCR4 immunotoxin targets human cutaneous T‐cell lymphoma

The majority of clinically diagnosed cutaneous T‐cell lymphomas (CTCL) highly express the cell‐surface markers CC chemokine receptor 4 (CCR4) and/or CD25. Recently, we have developed diphtheria toxin‐based recombinant Ontak®‐like human IL2 fusion toxin (IL2 fusion toxin) and anti‐human CCR4 immunoto...

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Bibliographic Details
Published in:Mol Oncol
Main Authors: Wang, Haoyu, Wang, Zhaohui, Zhang, Huiping, Qi, Zeng, Johnson, Ariel C., Mathes, David, Pomfret, Elizabeth A., Rubin, Erin, Huang, Christene A., Wang, Zhirui
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7191189/
https://ncbi.nlm.nih.gov/pubmed/32107846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12653
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