BCL-2 antagonism sensitizes cytotoxic T cell–resistant HIV reservoirs to elimination ex vivo

Curing HIV infection will require the elimination of a reservoir of infected CD4(+) T cells that persists despite HIV-specific cytotoxic T cell (CTL) responses. Although viral latency is a critical factor in this persistence, recent evidence also suggests a role for intrinsic resistance of reservoir...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Ren, Yanqin, Huang, Szu Han, Patel, Shabnum, Alberto, Winiffer D. Conce, Magat, Dean, Ahimovic, Dughan, Macedo, Amanda B., Durga, Ryan, Chan, Dora, Zale, Elizabeth, Mota, Talia M., Truong, Ronald, Rohwetter, Thomas, McCann, Chase D., Kovacs, Colin M., Benko, Erika, Wimpelberg, Avery, Cannon, Christopher, Hardy, W. David, Bosque, Alberto, Bollard, Catherine M., Jones, R. Brad
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7191002/
https://ncbi.nlm.nih.gov/pubmed/32027622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI132374
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