The β3-adrenergic receptor agonist mirabegron improves glucose homeostasis in obese humans

BACKGROUND: Beige adipose tissue is associated with improved glucose homeostasis in mice. Adipose tissue contains β3-adrenergic receptors (β3-ARs), and this study was intended to determine whether the treatment of obese, insulin-resistant humans with the β3-AR agonist mirabegron, which stimulates be...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Finlin, Brian S., Memetimin, Hasiyet, Zhu, Beibei, Confides, Amy L., Vekaria, Hemendra J., El Khouli, Riham H., Johnson, Zachary R., Westgate, Philip M., Chen, Jianzhong, Morris, Andrew J., Sullivan, Patrick G., Dupont-Versteegden, Esther E., Kern, Philip A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2020
Teme:
Clinical Medicine
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190997/
https://ncbi.nlm.nih.gov/pubmed/31961829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI134892
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