The β3-adrenergic receptor agonist mirabegron improves glucose homeostasis in obese humans

BACKGROUND: Beige adipose tissue is associated with improved glucose homeostasis in mice. Adipose tissue contains β3-adrenergic receptors (β3-ARs), and this study was intended to determine whether the treatment of obese, insulin-resistant humans with the β3-AR agonist mirabegron, which stimulates be...

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Vydáno v:J Clin Invest
Hlavní autoři: Finlin, Brian S., Memetimin, Hasiyet, Zhu, Beibei, Confides, Amy L., Vekaria, Hemendra J., El Khouli, Riham H., Johnson, Zachary R., Westgate, Philip M., Chen, Jianzhong, Morris, Andrew J., Sullivan, Patrick G., Dupont-Versteegden, Esther E., Kern, Philip A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2020
Témata:
Clinical Medicine
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190997/
https://ncbi.nlm.nih.gov/pubmed/31961829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI134892
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