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Pioglitazone does not synergize with mirabegron to increase beige fat or further improve glucose metabolism

BACKGROUND: Beige and brown adipose tissue (BAT) are associated with improved metabolic homeostasis. We recently reported that the β(3)-adrenergic receptor agonist mirabegron induced beige adipose tissue in obese insulin-resistant subjects, and this was accompanied by improved glucose metabolism. He...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Finlin, Brian S., Memetimin, Hasiyet, Zhu, Beibei, Confides, Amy L., Vekaria, Hemendra J., El Khouli, Riham H., Johnson, Zachary R., Westgate, Philip M., Chen, Jianzhong, Morris, Andrew J., Sullivan, Patrick G., Dupont-Versteegden, Esther E., Kern, Philip A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026187/
https://ncbi.nlm.nih.gov/pubmed/33571166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.143650
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