Pioglitazone does not synergize with mirabegron to increase beige fat or further improve glucose metabolism

BACKGROUND: Beige and brown adipose tissue (BAT) are associated with improved metabolic homeostasis. We recently reported that the β(3)-adrenergic receptor agonist mirabegron induced beige adipose tissue in obese insulin-resistant subjects, and this was accompanied by improved glucose metabolism. He...

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Vydáno v:JCI Insight
Hlavní autoři: Finlin, Brian S., Memetimin, Hasiyet, Zhu, Beibei, Confides, Amy L., Vekaria, Hemendra J., El Khouli, Riham H., Johnson, Zachary R., Westgate, Philip M., Chen, Jianzhong, Morris, Andrew J., Sullivan, Patrick G., Dupont-Versteegden, Esther E., Kern, Philip A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2021
Témata:
Clinical Medicine
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026187/
https://ncbi.nlm.nih.gov/pubmed/33571166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.143650
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