Pioglitazone does not synergize with mirabegron to increase beige fat or further improve glucose metabolism

BACKGROUND: Beige and brown adipose tissue (BAT) are associated with improved metabolic homeostasis. We recently reported that the β(3)-adrenergic receptor agonist mirabegron induced beige adipose tissue in obese insulin-resistant subjects, and this was accompanied by improved glucose metabolism. He...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:JCI Insight
Prif Awduron: Finlin, Brian S., Memetimin, Hasiyet, Zhu, Beibei, Confides, Amy L., Vekaria, Hemendra J., El Khouli, Riham H., Johnson, Zachary R., Westgate, Philip M., Chen, Jianzhong, Morris, Andrew J., Sullivan, Patrick G., Dupont-Versteegden, Esther E., Kern, Philip A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2021
Pynciau:
Clinical Medicine
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026187/
https://ncbi.nlm.nih.gov/pubmed/33571166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.143650
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