The neonatal microenvironment programs innate γδ T cells through the transcription factor STAT5

IL-17–producing RORγt(+) γδ T cells (γδT17 cells) are innate lymphocytes that participate in type 3 immune responses during infection and inflammation. Herein, we show that γδT17 cells rapidly proliferate within neonatal lymph nodes and gut, where, upon entry, they upregulate T-bet and coexpress IL-...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Kadekar, Darshana, Agerholm, Rasmus, Rizk, John, Neubauer, Heidi A., Suske, Tobias, Maurer, Barbara, Viñals, Monica Torrellas, Comelli, Elena M., Taibi, Amel, Moriggl, Richard, Bekiaris, Vasileios
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190909/
https://ncbi.nlm.nih.gov/pubmed/32281944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI131241
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares