Implications of STAT3 and STAT5 signaling on gene regulation and chromatin remodeling in hematopoietic cancer

STAT3 and STAT5 proteins are oncogenic downstream mediators of the JAK–STAT pathway. Deregulated STAT3 and STAT5 signaling promotes cancer cell proliferation and survival in conjunction with other core cancer pathways. Nuclear phosphorylated STAT3 and STAT5 regulate cell-type-specific transcription...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Leukemia
Egile Nagusiak: Wingelhofer, Bettina, Neubauer, Heidi A., Valent, Peter, Han, Xiaonan, Constantinescu, Stefan N., Gunning, Patrick T., Müller, Mathias, Moriggl, Richard
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Review Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6087715/
https://ncbi.nlm.nih.gov/pubmed/29728695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-018-0117-x
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