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TRPV4 helps Piezo1 put the squeeze on pancreatic acinar cells

Alterations in calcium signaling in pancreatic acinar cells can result in pancreatitis. Although pressure changes in the pancreas can elevate cytosolic calcium (Ca(2+)) levels, it is not known how transient pressure-activated elevations in calcium can cause prolonged calcium changes and consequent p...

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Bibliografische gegevens
Gepubliceerd in:J Clin Invest
Hoofdauteurs: Gorelick, Fred, Nathanson, Michael H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190901/
https://ncbi.nlm.nih.gov/pubmed/32281947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI136525
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