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TRPV4 helps Piezo1 put the squeeze on pancreatic acinar cells

Alterations in calcium signaling in pancreatic acinar cells can result in pancreatitis. Although pressure changes in the pancreas can elevate cytosolic calcium (Ca(2+)) levels, it is not known how transient pressure-activated elevations in calcium can cause prolonged calcium changes and consequent p...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Gorelick, Fred, Nathanson, Michael H.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190901/
https://ncbi.nlm.nih.gov/pubmed/32281947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI136525
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