Optogenetic stimulation of phosphoinositides reveals a critical role of primary cilia in eye pressure regulation

Glaucoma is a group of progressive optic neuropathies that cause irreversible vision loss. Although elevated intraocular pressure (IOP) is associated with the development and progression of glaucoma, the mechanisms for its regulation are not well understood. Here, we have designed CIBN/CRY2-based op...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Adv
Prif Awduron: Prosseda, Philipp P., Alvarado, Jorge A., Wang, Biao, Kowal, Tia J., Ning, Ke, Stamer, W. Daniel, Hu, Yang, Sun, Yang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Association for the Advancement of Science 2020
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190330/
https://ncbi.nlm.nih.gov/pubmed/32494665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay8699
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