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Optogenetic stimulation of phosphoinositides reveals a critical role of primary cilia in eye pressure regulation

Glaucoma is a group of progressive optic neuropathies that cause irreversible vision loss. Although elevated intraocular pressure (IOP) is associated with the development and progression of glaucoma, the mechanisms for its regulation are not well understood. Here, we have designed CIBN/CRY2-based op...

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Detalles Bibliográficos
Publicado en:Sci Adv
Main Authors: Prosseda, Philipp P., Alvarado, Jorge A., Wang, Biao, Kowal, Tia J., Ning, Ke, Stamer, W. Daniel, Hu, Yang, Sun, Yang
Formato: Artigo
Idioma:Inglês
Publicado: American Association for the Advancement of Science 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190330/
https://ncbi.nlm.nih.gov/pubmed/32494665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay8699
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