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Optogenetic stimulation of phosphoinositides reveals a critical role of primary cilia in eye pressure regulation

Glaucoma is a group of progressive optic neuropathies that cause irreversible vision loss. Although elevated intraocular pressure (IOP) is associated with the development and progression of glaucoma, the mechanisms for its regulation are not well understood. Here, we have designed CIBN/CRY2-based op...

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Publicado en:Sci Adv
Autores principales: Prosseda, Philipp P., Alvarado, Jorge A., Wang, Biao, Kowal, Tia J., Ning, Ke, Stamer, W. Daniel, Hu, Yang, Sun, Yang
Formato: Artigo
Lenguaje:Inglês
Publicado: American Association for the Advancement of Science 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190330/
https://ncbi.nlm.nih.gov/pubmed/32494665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay8699
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