Click chemistry-facilitated comprehensive identification of proteins adducted by antimicrobial 5-nitroimidazoles for discovery of alternative drug targets against giardiasis

Giardiasis and other protozoan infections are major worldwide causes of morbidity and mortality, yet development of new antimicrobial agents with improved efficacy and ability to override increasingly common drug resistance remains a major challenge. Antimicrobial drug development typically proceeds...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Lauwaet, Tineke, Miyamoto, Yukiko, Ihara, Sozaburo, Le, Christine, Kalisiak, Jarosław, Korthals, Keith A., Ghassemian, Majid, Smith, Diane K., Sharpless, K. Barry, Fokin, Valery V., Eckmann, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190177/
https://ncbi.nlm.nih.gov/pubmed/32302296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0008224
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