Evaluation of canonical Hedgehog signaling pathway inhibition in canine osteosarcoma

Canine osteosarcoma (OSA), the most common canine primary bone malignancy, has a highly aggressive biologic behavior. Despite current standard of care therapies, including amputation and adjuvant chemotherapy, most dogs still succumb to metastatic disease. Further investigations into molecular mecha...

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Pubblicato in:PLoS One
Autori principali: Baldanza, Vincent E., Rogic, Anita, Yan, Weiwei, Levine, Corri B., Levine, Roy A., Miller, Andrew D., McCleary-Wheeler, Angela L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190150/
https://ncbi.nlm.nih.gov/pubmed/32348319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0231762
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