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Evaluation of canonical Hedgehog signaling pathway inhibition in canine osteosarcoma
Canine osteosarcoma (OSA), the most common canine primary bone malignancy, has a highly aggressive biologic behavior. Despite current standard of care therapies, including amputation and adjuvant chemotherapy, most dogs still succumb to metastatic disease. Further investigations into molecular mecha...
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| Veröffentlicht in: | PLoS One |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7190150/ https://ncbi.nlm.nih.gov/pubmed/32348319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0231762 |
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