Canonical and noncanonical Hedgehog pathway in the pathogenesis of multiple myeloma

The Hedgehog (Hh) pathway is required for cell-fate determination during the embryonic life, as well as cell growth and differentiation in the adult organism, where the inappropriate activation has been implicated in several cancers. Here we demonstrate that Hh signaling plays a significant role in...

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Main Authors: Blotta, Simona, Jakubikova, Jana, Calimeri, Teresa, Roccaro, Aldo M., Amodio, Nicola, Azab, Abdel Kareem, Foresta, Umberto, Mitsiades, Constantine S., Rossi, Marco, Todoerti, Katia, Molica, Stefano, Morabito, Fortunato, Neri, Antonino, Tagliaferri, Piersandro, Tassone, Pierfrancesco, Anderson, Kenneth C., Munshi, Nikhil C.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2012
Teme:
Lymphoid Neoplasia
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525024/
https://ncbi.nlm.nih.gov/pubmed/22821765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-07-368142
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