Development of CRISPR as an Antiviral Strategy to Combat SARS-CoV-2 and Influenza

The coronavirus disease 2019 (COVID-19) pandemic, caused by the SARS-CoV-2 virus, has highlighted the need for antiviral approaches that can target emerging viruses with no effective vaccines or pharmaceuticals. Here, we demonstrate a CRISPR-Cas13-based strategy, PAC-MAN (prophylactic antiviral CRIS...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Abbott, Timothy R., Dhamdhere, Girija, Liu, Yanxia, Lin, Xueqiu, Goudy, Laine, Zeng, Leiping, Chemparathy, Augustine, Chmura, Stephen, Heaton, Nicholas S., Debs, Robert, Pande, Tara, Endy, Drew, La Russa, Marie F., Lewis, David B., Qi, Lei S.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Inc. 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7189862/
https://ncbi.nlm.nih.gov/pubmed/32353252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.04.020
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