Widespread and tissue-specific expression of endogenous retroelements in human somatic tissues

BACKGROUND: Endogenous retroelements (EREs) constitute about 42% of the human genome and have been implicated in common human diseases such as autoimmunity and cancer. The dominant paradigm holds that EREs are expressed in embryonic stem cells (ESCs) and germline cells but are repressed in different...

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Detalhes bibliográficos
Publicado no:Genome Med
Main Authors: Larouche, Jean-David, Trofimov, Assya, Hesnard, Leslie, Ehx, Gregory, Zhao, Qingchuan, Vincent, Krystel, Durette, Chantal, Gendron, Patrick, Laverdure, Jean-Philippe, Bonneil, Éric, Côté, Caroline, Lemieux, Sébastien, Thibault, Pierre, Perreault, Claude
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7189544/
https://ncbi.nlm.nih.gov/pubmed/32345368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-020-00740-7
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