Anti-HER2 induced myeloid cell alterations correspond with increasing vascular maturation in a murine model of HER2+ breast cancer

BACKGROUND: Therapy targeted to the human epidermal growth factor receptor type 2 (HER2) is used in combination with cytotoxic therapy in treatment of HER2+ breast cancer. Trastuzumab, a monoclonal antibody that targets HER2, has been shown pre-clinically to induce vascular changes that can increase...

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Udgivet i:BMC Cancer
Main Authors: Bloom, Meghan J., Jarrett, Angela M., Triplett, Todd A., Syed, Anum K., Davis, Tessa, Yankeelov, Thomas E., Sorace, Anna G.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7189470/
https://ncbi.nlm.nih.gov/pubmed/32345237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-06868-4
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