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Mathematical modelling of trastuzumab-induced immune response in an in vivo murine model of HER2+ breast cancer

The goal of this study is to develop an integrated, mathematical–experimental approach for understanding the interactions between the immune system and the effects of trastuzumab on breast cancer that overexpresses the human epidermal growth factor receptor 2 (HER2+). A system of coupled, ordinary d...

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Bibliographic Details
Published in:Math Med Biol
Main Authors: Jarrett, Angela M, Bloom, Meghan J, Godfrey, Wesley, Syed, Anum K, Ekrut, David A, Ehrlich, Lauren I, Yankeelov, Thomas E, Sorace, Anna G
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6737347/
https://ncbi.nlm.nih.gov/pubmed/30239754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/imammb/dqy014
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