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Serine-dependent redox homeostasis regulates glioblastoma cell survival
BACKGROUND: The amino acid serine is an important substrate for biosynthesis and redox homeostasis. We investigated whether glioblastoma (GBM) cells are dependent on serine for survival under conditions of the tumour microenvironment. METHODS: Serine availability in GBM cells was modulated pharmacol...
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| Pubblicato in: | Br J Cancer |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7188854/ https://ncbi.nlm.nih.gov/pubmed/32203214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-0794-x |
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