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Phase 1 study of napabucasin, a cancer stemness inhibitor, in patients with advanced solid tumors
PURPOSE: Napabucasin is a cancer stemness inhibitor that targets a number of oncogenic pathways, including signal transducer and activator of transcription 3 (STAT3). Phase 1/2 studies suggest tolerability and anti-tumor activity in various types of cancer; a Phase 3 study of napabucasin plus standa...
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| izdano v: | Cancer Chemother Pharmacol |
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| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Springer Berlin Heidelberg
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7188713/ https://ncbi.nlm.nih.gov/pubmed/32236642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-020-04059-3 |
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