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Risk Variants with Opposing Functional Effects Result in Hypomorphic Expression of TNIP1 and Other Genes within a 3D Chromatin Network
OBJECTIVE: Genetic variants in the region of TNFAIP3 interacting protein 1 (TNIP1) are associated with autoimmune disease and reduced TNIP1 gene expression. This study aimed to define the functional genetic mechanisms driving TNIP1 hypomorphic expression imparted by the SLE-associated TNIP1 H1 risk...
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| Publicado no: | Arthritis Rheumatol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7188567/ https://ncbi.nlm.nih.gov/pubmed/31804013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.41188 |
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