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Use of next-generation DNA sequencing to analyze genetic variants in rheumatic disease

Next-generation DNA sequencing has revolutionized the field of genetics and genomics, providing researchers with the tools to efficiently identify novel rare and low frequency risk variants, which was not practical with previously available methodologies. These methods allow for the sequence capture...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Wiley, Graham B, Kelly, Jennifer A, Gaffney, Patrick M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396863/
https://ncbi.nlm.nih.gov/pubmed/25789374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-014-0490-4
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