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Use of next-generation DNA sequencing to analyze genetic variants in rheumatic disease

Next-generation DNA sequencing has revolutionized the field of genetics and genomics, providing researchers with the tools to efficiently identify novel rare and low frequency risk variants, which was not practical with previously available methodologies. These methods allow for the sequence capture...

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Détails bibliographiques
Publié dans:Arthritis Res Ther
Auteurs principaux: Wiley, Graham B, Kelly, Jennifer A, Gaffney, Patrick M
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396863/
https://ncbi.nlm.nih.gov/pubmed/25789374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-014-0490-4
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