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Use of next-generation DNA sequencing to analyze genetic variants in rheumatic disease

Next-generation DNA sequencing has revolutionized the field of genetics and genomics, providing researchers with the tools to efficiently identify novel rare and low frequency risk variants, which was not practical with previously available methodologies. These methods allow for the sequence capture...

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Dettagli Bibliografici
Pubblicato in:Arthritis Res Ther
Autori principali: Wiley, Graham B, Kelly, Jennifer A, Gaffney, Patrick M
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396863/
https://ncbi.nlm.nih.gov/pubmed/25789374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-014-0490-4
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